The aging population and inherently associated degenerative diseases indicate an unmet need to develop and commercialize innovative tissue regenerative products.
In the area of Life Sciences, tissue engineering and orthobiology in particular have gained substantial interest. Tissue engineering includes the development of biological artificial substitutes to create new tissue to support, repair or replace lost or damaged tissue and organs.
Living tissues like skin, bone, cartilage, kidney, nerves or blood vessels can be created for therapeutic purposes. This enables, for example, the treatment of burn wounds, cardiovascular diseases and degenerative diseases such as intervertebral disc degeneration, spondylolysis and osteoarthritis
Tissue engineering combines biomaterials with patient derived cells. Due to its importance in cell signaling, biomaterials play a pivotal role
Orthobiology combines advances in biotechnology with biomaterial sciences and tissue biology to promote the body’s natural capacity to regenerate and repair musculoskeletal tissue like bone and cartilage.
As much as the implant influences the healing environment, the healing environment influences the biodegradability, safety and performance of the implant. Fundamental knowledge on product development and the interaction of biomaterials and their intended implantation environment are therefore at the heart of orthobiology and tissue engineering.